PERINATAL DETERMINANTS OF CARDIOVASCULAR PATHOLOGY IN CHILDREN WITH MINOR ANOMALIES OF CARDIAC DEVELOPMENT: A CLINICAL AND STATISTICAL STUDY

Autores

DOI:

https://doi.org/10.18623/rvd.v23.4889

Palavras-chave:

Minor Anomalies of Cardiac Development, Connective Tissue Dysplasia, Perinatal Factors, Cardiovascular Pathology, Children

Resumo

Objective: to assess the impact of perinatal factors and comorbid conditions on the development of cardiovascular pathology in children with minor anomalies of cardiac development (MACD). Materials and methods: a clinical and statistical examination of children with MACD and varying degrees of connective tissue dysplasia (CTD) was conducted using relative and attributable risk indicators. Results: maternal anemia, gestosis, infections, complicated delivery, and hereditary burden showed the strongest association with cardiovascular pathology. Conclusions: perinatal factors and comorbid diseases significantly increase the risk of cardiovascular pathology in children with MACD.

Referências

Abdukadirova N. Connective tissue dysplasia as a component in the development of pathology of certain body systems (literature review). Medical Science of Uzbekistan. 2025;(1):27–34. https://doi.org/10.56121/2181-3612-2025-1-27-34.

Abdullaeva D.G.. Abdullaeva D.T.. Mirrokhimova M.H.. Kurbanova D.R. Factors that affect the development of functional heart disorders in children with undifferentiated connective tissue dysplasia // The Bioscan. – 2025. – Vol. 20. Suppl. 2. – P. 520–523.

Achilova F.A. Risk factors for the development of minor cardiac anomalies in children. International Journal of Scientific Pediatrics. 2025;4(2):939–942. https://doi.org/10.56121/2181-2926-2025-4-2-939-942.

Akhrarova F.M. Indicators of hydroxyproline levels and mineral imbalance in children with clinical manifestations of cardiac connective tissue dysplasia. Journal of Biomedicine and Practice. 2021;1(3/1):387–395. https://doi.org/10.26739/2181-9300-2021-3-58.

Akhrarova F.M. Assessment of matrix metalloproteinase activity in cardiac remodeling in a child with connective tissue dysplasia (clinical case). EJMNS. 2025;(3–2). Available at: https://cyberleninka.ru/article/n/otsenka-aktivnosti-matriksnyh-metalloproteinaz-pri-remodelirovanii-serdtsa-u-rebenka-s-displaziey-soedinitelnoy-tkani-klinicheskiy.

Mahmoud Abd Elsalam S.. et al. Early detection of fetal minor cardiac anomalies in high-risk pregnant women using Doppler measurements of ductus venosus // Egyptian Journal of Medical Research. – 2025. – Vol. 6. No. 3. – P. 193–205.

Timofeev E.V.. Malev E.G.. Zemtsovsky E.V. Small heart anomalies as cardiac manifestations of hereditary connective tissue disorders // Pediatrician (St. Petersburg). – 2020. – Vol. 11. No. 5. – P. 5–12.

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Publicado

2026-03-05

Como Citar

Makhmudjanovna, A. F., & Abdugaparovna, A. N. (2026). PERINATAL DETERMINANTS OF CARDIOVASCULAR PATHOLOGY IN CHILDREN WITH MINOR ANOMALIES OF CARDIAC DEVELOPMENT: A CLINICAL AND STATISTICAL STUDY. Veredas Do Direito , 23, e234889. https://doi.org/10.18623/rvd.v23.4889

Edição

v. 23 (2026): Veredas do Direito, v. 23, 2026

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Artigos

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