BENIGN FIBROUS HISTIOCYTOMA (DERMATOFIBROMA): A CASE REPORT

Autores

  • Amani Omar Safdar Collage of Medicine, Umm Al-Qura University
  • Ola Abdullah Altwyjri College of Medicine, Umm Al-Qura University
  • Fahad Matouq Alkhuzaei General Surgery resident, King Faisal Hospital
  • Rani A. Alsairafi Surgery department, College of Medicine, Umm Al Qura University
  • Heba B. AlQethami King Faisal Hospital
  • Abdulaziz K. Alsamti King Faisal Hospital

DOI:

https://doi.org/10.18623/rvd.v23.n3.4612

Palavras-chave:

Benign fibrous histiocytoma, Dermatofibroma, Case report, Spindle cell tumor, Immunohistochemistry

Resumo

Background: Benign fibrous histiocytoma (BFH), also known as dermatofibroma, is a common benign cutaneous mesenchymal tumor. Despite its benign nature, it may mimic other spindle cell lesions clinically and histologically, necessitating accurate diagnostic evaluation. Case Presentation: We report a case of a patient presenting with a slowly growing, painless cutaneous dermal nodule. Complete local surgical excision was performed for diagnostic and therapeutic purposes. Histopathological Findings: Microscopic examination revealed a dermal-based spindle cell proliferation arranged in a storiform pattern, composed of fibroblast-like cells without cytologic atypia, necrosis, or increased mitotic activity. Immunohistochemical analysis showed positivity for CD68 and negativity for CD34, supporting the diagnosis of benign fibrous histiocytoma and excluding malignant spindle cell neoplasms. Conclusion: This case highlights the importance of histopathological evaluation supported by immunohistochemical analysis in the accurate diagnosis of benign fibrous histiocytoma. In the present case, complete surgical excision was followed by a favorable outcome, reinforcing the value of a systematic diagnostic approach.

Referências

Kaur, H., Kaur, J., Gill, K. S., Mannan, R., & Arora, S. (2014). Subcutaneous dermatofibroma: A rare case report with review of the literature. Journal of Clinical and Diagnostic Research, 8(4), FD01–FD02. https://doi.org/10.7860/JCDR/2014/6586.4204

Scolozzi, P., Lombardi, T., & Jaques, B. (2007). Subcutaneous benign fibrous histiocytoma of the cheek: Case report and review of the literature. Acta Otorhinolaryngologica Italica, 27(2), 90–93.

Bulut, T., & Çelik, B. (2018). Clear cell dermatofibroma on the chest wall: A case report and its diagnostic traps. Indian Dermatology Online Journal, 9(4), 265–267. https://doi.org/10.4103/idoj.IDOJ_289_17

Won, K. Y., Park, S. Y., Jin, W., & Lew, B. L. (2018). Dermatofibroma: Sonographic findings and pathologic correlation. Acta Radiologica, 59(4), 454–459. https://doi.org/10.1177/0284185117721263

Han, T. Y., Chang, H. S., Lee, J. H. K., Lee, W. M., & Son, S. J. (2011). A clinical and histopathological study of 122 cases of dermatofibroma (benign fibrous histiocytoma). Annals of Dermatology, 23(2), 185–192. https://doi.org/10.5021/ad.2011.23.2.185

Cohen, P. R., Erickson, C. P., & Calame, A. (2019). Atrophic dermatofibroma: A comprehensive literature review. Dermatology and Therapy, 9(3), 449–468. https://doi.org/10.1007/s13555-019-0309-y

Downloads

Publicado

2026-01-29

Como Citar

Safdar, A. O., Altwyjri, O. A., Alkhuzaei, F. M., Alsairafi, R. A., AlQethami, H. B., & Alsamti, A. K. (2026). BENIGN FIBROUS HISTIOCYTOMA (DERMATOFIBROMA): A CASE REPORT. Veredas Do Direito , 23, e234612. https://doi.org/10.18623/rvd.v23.n3.4612

Edição

v. 23 (2026): Veredas do Direito, v. 23, 2026

Seção

Artigos

Licença

Submeto (emos) o presente trabalho, texto original e inédito, de minha (nossa) autoria, à  avaliação de Veredas do Direito - Revista de Direito, e concordo (amos) que os direitos autorais a ele referentes se tornem propriedade exclusiva  da Revista Veredas, sendo vedada qualquer  reprodução total ou parcial, em qualquer outra parte ou outro meio de divulgação impresso ou eletrônico, dissociado de Veredas do Direito, sem que a necessária e prévia autorização seja solicitada por escrito e obtida junto ao Editor-gerente. Declaro (amos) ainda que não existe conflito de interesse entre o tema abordado, o (s) autor (es) e empresas, instituições ou indivíduos.

Reconheço (Reconhecemos) ainda que Veredas está licenciada sob uma LICENÇA CREATIVE COMMONS:

Licença Creative Commons Attribution 3.0