EFFICACY OF POVIDONE-IODINE VS CHLORHEXIDINE TO REDUCE SURGICAL SITE INFECTION IN PATIENTS UNDERGOING CESAREAN SECTION: A COMPARATIVE STUDY
DOI:
https://doi.org/10.18623/rvd.v23.5985Keywords:
Cesarean Section, Surgical site Infection (SSI), Chlorhexidine, Povidone-iodine, Maternal Risk Factors (Age and BMI)Abstract
Background: Cesarean section is a common surgical procedure that is performed in the world and it is linked to a high risk of surgical site infections (SSIs). Skin antisepsis before the operation is significant in the prevention of SSIs. There is however, doubt on the comparative efficacy of povidone-iodine and chlorhexidine in the cesarean section. Objective: This study aims at comparing incidences of surgical site infection in patients undergoing cesarean section using povidone-iodine and chlorhexidine. Methodology: This randomized controlled trial was conducted in the Department of Obstetrics and Gynaecology of Sughra Shafi Medical Complex, Narowal. A total of 700 patients undergoing elective cesarean section were enrolled and randomly divided into two groups (n=350 each). Group A received chlorhexidine (0.5%) and Group B received povidone-iodine for preoperative skin preparation. Patients were followed for 30 days postoperatively for development of SSI. Data were analyzed using SPSS version 20.0. Results: The frequency of SSI was lower in the chlorhexidine group (4.3%) compared to the povidone-iodine group (8.0%), showing a statistically significant difference (p ≤ 0.05). Higher maternal age and increased BMI were significantly associated with increased SSI rates. Conclusion: Chlorhexidine is more effective than povidone-iodine in reducing surgical site infections in cesarean section. Maternal age and BMI are important risk factors influencing SSI occurrence.
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